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CLINICALLY RELEVANT ANTIMICROBIAL SPECTRUM OF THE MACROLIDES As discussed below in the sections on pharmacokinetics and pharmacodynamics, predicting in-vivo efficacy on the basis solely of extracellular levels of free drug is difficult with MLS compounds.

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152 Urodynamics we would prefer to use suprapubic catheters (two epidural catheters, 350358 (2002).


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Fig. Because vol- ume decreases with increasing pressure, these definitions contain negative signs to make the compressibilities positive. In view of the definition (5.

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